17‐β‐Estradiol upregulates the stress response in Candida albicans: Implications for microbial virulence

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17-beta-estradiol upregulates the stress response in Candida albicans: implications for microbial virulence.

OBJECTIVE The influence of 17-beta-estradiol on the stress response of Candida albicans was studied. METHODS The survival of clinical isolates of C. albicans treated with 17-beta-estradiol after heat and oxidative stress was measured by viable plate counts. Cellular proteins were analyzed via SDS-PAGE. RESULTS The heat stress response induced by 17-beta-estradiol in C. albicans grown at 25 ...

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Role of retrograde trafficking in stress response, host cell interactions, and virulence of Candida albicans.

In Saccharomyces cerevisiae, the vacuolar protein sorting complexes Vps51/52/53/54 and Vps15/30/34/38 are essential for efficient endosome-to-Golgi complex retrograde transport. Here we investigated the function of Vps15 and Vps51, representative members of these complexes, in the stress resistance, host cell interactions, and virulence of Candida albicans. We found that C. albicans vps15Δ/Δ an...

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ژورنال

عنوان ژورنال: Infectious Diseases in Obstetrics and Gynecology

سال: 1998

ISSN: 1064-7449,1098-0997

DOI: 10.1002/(sici)1098-0997(1998)6:4<176::aid-idog7>3.3.co;2-m